As an Integrative Cardiologist I have seen the damage due to oxidative stress in my patients for decades. Nrf2 activation is the most efficient way to suppress the damage caused by oxidative stress. This is the reason I've been so committed to sharing Nrf2 and Grandevity with the world.

I have been an international speaker on the topic of Nrf2 for more than a decade. A great deal has changed with Nrf2 technology since it was introduced in the early 2000's.

My passion to reduce cardiovascular risk leads me to only recommend the best cutting-edge products and technologies.

Older Nrf2 activating products do not have all the benefits of Grandevity.  Some of the older Nrf2 activators are poorly absorbed in the gut, thus reducing their effectiveness in activating Nrf2 in vivo. Further, as our understanding of the Nrf2 pathway has grown, we are now able to activate Nrf2 at multiple points in the pathway as well as decrease Nrf2's degradation, allowing it to remain active longer in the nucleus of the cell. Today, we are at the peak of research on Nrf2 activation. We now know that not all Nrf2 activators are created equally. Many of the older Nrf2 activators are burdened with a problem called 'electrophilic toxicity.' Older Nrf2 activators increase the production of antioxidant enzymes like catalase, superoxide dismutase, and glutathione but some of the ingredients in these older Nrf2 activating preparations cause 'electrophilic toxicity' in the mitochondria which chews up the anti-oxidant enzymes, like glutathione, nearly as quickly as the cell makes them, thus the net production of the anti-oxidant enzymes is nil. Grandevity does not have this problem with electrophilic toxicity, so the anti-oxidant enzymes produced by Grandevity are in high enough amounts to seek and destroy the free radicals that are causing oxidative stress, just as these enzymes were designed to do by nature. The net effect of anti-oxidant production is much better with Grandevity than older Nrf2 activators. Grandevity is a 'cleaner' Nrf2 activator in many respects. Many people take multiple products in an attempt to reduce oxidative stress, enhance mitochondrial function.  Grandevity should be the one supplement you take every day.   

I received my MD and completed my Cardiology Fellowship at the University of Minnesota. I practiced Invasive Cardiology for 20 years. Coronary Heart Disease was the primary health issue I treated. Trying to get patients to address their heart disease risk factors was not always an easy task. Cardiovascular health is of critical importance as the American Heart Association states that someone dies of Cardiovascular Disease every 40 seconds. Not fulfilled with traditional medicine, I pursued a fellowship in Anti-Aging and Regenerative Medicine through the American Academy of Anti-Aging Medicine and further training and certification in Advanced Metabolic Cardiovascular Medicine through George Washington University. I am passionate about preventing cardiovascular disease, helping people achieve optimal health, and maximizing longevity.

I'm grateful to work with Veronica Gordon, Lifecoach, in our wellness center in Carlsbad, CA.  She makes such a difference with the clients.  It's one thing to tell someone what they need to do, it's another to get them to do it. Veronica's passion to help others get to their goal is the 'secret formula' that makes the approach of Longevity Personalized different from other longevity centers and what gets the success we enjoy.  I'm so grateful for her incredible contributions to the success of Longevity Personalized and the Grandevity project. My beautiful wife Veronica's creative spirit led to the name Grandevity and the design and theme of this website.

I enjoy the outdoors, hikes in the mountains, walks on the beach, and anything that gets me out into nature. I take every measure I can to insure my ability to continue to do these things will be there for many years to come. I have genetic predispositions to several diseases, but as I've learned, "Your genes do not need to be your destiny." Your epigenome controls the expression of your genes (epigenetics) and Grandevity has beneficial effects on thousands of genes.  Heart health begins with a heart-healthy anti-inflammatory diet, appropriate targeted heart health supplements, exercise, and a healthy lifestyle. Grandevity is an essential part of my longevity plan.

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"Your genes are not your destiny."

~  Mark Gordon, MD, FACC

    The Longevity Cardiologist